Which symptom would suggest a worsening condition for a patient with COPD?

Persistent breathlessness is a significant symptom that indicates a worsening condition in a patient with Chronic Obstructive Pulmonary Disease (COPD). In the context of COPD, patients may experience varying degrees of shortness of breath, especially during physical activities or when exacerbations occur. The presence of persistent breathlessness suggests that the patient's respiratory function may be declining, and it could indicate a potential exacerbation, increased airway resistance, or reduced oxygenation.

Monitoring breathlessness is crucial in COPD management because it can affect a patient's overall quality of life and may necessitate adjustments in treatment or lifestyle modifications. In contrast, improved physical endurance, clear mucus secretion, and regular sleep patterns typically reflect stability or improvement in a patient’s condition, and do not suggest worsening.