What is one of the major factors contributing to the development of cancer?

Genetic mutations affecting normal cell functions is a critical factor in the development of cancer because these mutations can lead to uncontrolled cell division and proliferation. In a healthy body, there are mechanisms in place that regulate cell growth and repair damaged DNA. When genetic mutations occur, they can disrupt these regulatory processes, potentially leading to the formation of tumors as cells begin to grow and divide uncontrollably. This can happen through a variety of pathways, including the activation of oncogenes (which promote cell division) and the inactivation of tumor suppressor genes (which normally inhibit cell division). Overall, the genetic basis of cancer emphasizes the importance of both inherited mutations and those acquired through environmental factors or lifestyle choices, making it a central focus in understanding cancer development.