What is a main complication associated with shingles?

Post herpetic neuralgia (PHN) is a significant complication associated with shingles, which is caused by the varicella-zoster virus. After the initial shingles rash has healed, some patients experience persistent pain that can last for weeks, months, or even years. This pain can be severe and debilitating, often described as burning, stabbing, or aching. The development of PHN is more common in older adults and can greatly affect a person's quality of life, leading to difficulties in daily activities and mental health issues due to chronic pain.

While skin infections can occur at the site of shingles lesions, they are generally considered less common than the occurrence of post herpetic neuralgia. Reduced mobility and hair loss are not direct complications associated with shingles, making them less relevant to this specific question. Therefore, post herpetic neuralgia stands out as the primary and most concerning complication arising from shingles.