What are subcutaneous nodules in the context of rheumatic fever?

Subcutaneous nodules in the context of rheumatic fever refer to firm lumps that form under the skin due to inflammation associated with this condition. These nodules, often referred to as rheumatic nodules, typically appear in areas such as the elbows, knees, and sometimes over bony prominences. They are one of the clinical manifestations of rheumatic fever, which is an inflammatory disease that can occur following a streptococcal throat infection.

The formation of these nodules is an immune response to the body's attempt to combat the inflammatory process of rheumatic fever. They are generally painless and can vary in size, reflecting the underlying inflammatory activity. Recognizing these nodules is important in diagnosing rheumatic fever and understanding its systemic effects on the body, particularly on the heart and joints.

This option aligns correctly with the pathophysiology of rheumatic fever and helps illustrate how inflammation can manifest in physical symptoms.